Baltimore · ACMG Annual Meeting 2026

The first AI agent that
reasons over your variants.

Not another lookup tool. Deriva is production-ready — plug it into your existing workflow and watch it actively read, cross-validate, and classify your cases in real time.

Get first access Watch it work
See it classify a real variant below
Live Demo

Watch it classify a real VUS.

Not a narrated walkthrough — a live hereditary cancer variant reasoned through in real time, every VCEP criterion mapped, full audit trail generated.

app.deriva.ai · STXBP1:c.874C>T · Live Reasoning
● Pathogenic
p.Arg292Cys
Missense
VCEP: PS3 · PS2 · BP4
PS2
PS3
PM1
BP4
PP3
Play Demo — 8 min
Live classification · No narration overlay
25%
50%
75% — high intent signal
Complete
01
Live agent reasoning
Watch it read and connect evidence in real time — not pre-rendered, not cached.
02
VCEP criteria + live literature
Covers the latest VCEP guidelines, recent papers, and lab evidence — cross-validated simultaneously, not one-by-one.
03
Full audit trail
Every reasoning step recorded — ready for clinical sign-off, appeal, or co-authorship.
Built for production

Plug in. Get results. No retraining.

Deriva integrates into your existing lab workflow — no rip-and-replace, no lengthy deployment.

Step 01
🧬
Reads live evidence

Reads the latest VCEP guidelines, counts probands across recent papers, cross-references lab history — then reasons across all of it together to classify a criterion. Not lookup. Synthesis.

Step 02
🔗
Works while you sleep

Fully cloud-based and available 24/7 — run analyses overnight, come back to results. No local install, no compute limits, no waiting.

Step 03
Drops into your workflow

No need to change anything or install new tools. We integrate directly with your variant analysis platform — your team keeps working the way they already do.

Step 04
⚙️
Customize at scale

Teach it like you'd onboard a new fellow FACMG — in plain language. Tell it your SOPs, your policies, your edge cases — and it reasons accordingly, every time.

From the founder

Built for this room.
Missed the flight.

A last-minute canceled flight kept our team out of Baltimore. We built Deriva specifically for clinical genomics teams — AI that actually fits into a lab manager's day, not a proof-of-concept. Production-ready, not just buzzwords.

N
Nizar Jubran
CEO & Founder, Deriva.ai

A canceled flight kept us from Baltimore this year — genuinely gutting, because we built something specifically for this room.

We were ready to show the first General AI Agent for genomics — production-ready, ready to integrate into your existing workflow today.

This isn't a dashboard spitting out cached results. Deriva actively reads, understands, and reasons — across VCEP guidelines, the newest literature, and your lab's history.

I believe this is the next paradigm shift in how genomics teams work. And I personally respond to every registration within 24 hours.

Nizar Jubran
CEO & Founder
For lab managers & clinical leads

Ready to integrate AI into your variant workflow?

Deriva is production-ready and built for teams that want real AI — not demos, not pilots that never ship. Register to get early access and a direct conversation with our team.

Get a significant edge — teams using Deriva catch what others miss, faster
Scale accuracy and volume — handle more cases without compromising quality
Elevate every analyst — your whole team reasons at the level of your best
No rip-and-replace — works alongside what you already have
Direct line to Nizar — every registration gets a personal response within 24h
Early access — limited onboarding capacity
Get First Access
Nizar responds within 24 hours.
Work email gets priority onboarding

No commitment, no sales pitch unless you ask for one. Just a conversation about your workflow.

Request received — thank you!

We'll review your request and reach out within 24 hours.
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